Chronic changes of hematocrit value alter blood pressure and glomerular filtration in spontaneously hypertensive rats

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Chronic Changes of Hematocrit Value Alter Blood Pressure and Glomerular Filtration in Spontaneously Hypertensive Rats

Many studies in hypertensive humans and animals have shown that increased blood viscosity is in direct relation with essential hypertension. The aim of our studies was to investigate the effects of chronic hematocrit value changes on arterial blood pressure and kidney function in genetically induced hypertension. To this end, we studied the effects of several interventions, designed to increase...

متن کامل

Blood pressure and indices of glomerular filtration area in hypertensive and normotensive Prague rats.

The involvement of the kidney in the pathogenesis of hypertension has long been recognised, although the specific renal mechanisms underlying this phenomenon are still unknown. A current hypothesis attributes hypertension to a reduction in glomerular filtration area by glomerular loss. The present study analyses the relationship between glomerular number and volume and conscious systolic blood ...

متن کامل

Thromboxane synthesis and blood pressure in spontaneously hypertensive rats.

The present study examines effects of administration of OKY 046, an inhibitor of thromboxane synthesis, for 100 days on systemic blood pressure and renal function in spontaneously hypertensive rats and in normotensive control rats. Untreated spontaneously hypertensive rats had higher values for thromboxane excretion in the urine and higher values for blood pressure than did normotensive control...

متن کامل

Vasopressin and Blood Pressure in Spontaneously Hypertensive Rats

In conscious, unrestrained spontaneously hypertensiTe rats (SHR), mean arterial blood pressure (MAP) increased from a pretreatment value of 150 ± 4 to 179 ± 7 mm Hg within 10 min (p < 0.01) following an intracerebroventricular (I.C.T.) Injection of captopril (2 mg/kg body weight), and the plasma vasopressin concentration was increased eightfold (p < 0.01). MAP then fell to 131 ± 5 mm Hg at 120 ...

متن کامل

Blood Pressure Responses of Conscious Normotensive and Spontaneously Hypertensive Rats

In conscious spontaneously hypertensive rats, intracerebroTentricular injection of captopril (2 rag/kg) resulted in a rapid hypotenshe response that lasted several hours. The same dose given by Intracerebroventricular injection had no significant effect on blood pressure (BP) of normotensive Wistar-Kyoto (WK) rats over 7 hours. There was no significant change in BP of conscious spontaneously hy...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Acta veterinaria (Beograd)

سال: 2012

ISSN: 0567-8315,1820-7448

DOI: 10.2298/avb1201027m